David C Currow Selected Research

Cachexia

1/2023	Phase II, double blind, placebo controlled, multi-site study to evaluate the safety, feasibility and desirability of conducting a phase III study of anamorelin for anorexia in people with small cell lung cancer: A study protocol (LUANA trial).
1/2021	Quality of Life and Symptom Burden Improve in Patients Attending a Multidisciplinary Clinical Service for Cancer Cachexia: A Retrospective Observational Review.
11/2018	Efficacy of Anamorelin, a Novel Non-Peptide Ghrelin Analogue, in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC) and Cachexia-Review and Expert Opinion.
8/2017	The emerging role of anamorelin hydrochloride in the management of patients with cancer anorexia-cachexia.
4/2016	Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials.
4/2014	Anamorelin hydrochloride in the treatment of cancer anorexia-cachexia syndrome.

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David C Currow Research Topics

Disease

80	Dyspnea (Shortness of Breath) 03/2024 - 09/2003
80	Neoplasms (Cancer) 01/2023 - 02/2007
29	Chronic Obstructive Pulmonary Disease (COPD) 03/2024 - 09/2003
29	Pain (Aches) 01/2023 - 02/2006
22	Death (Near-Death Experience) 01/2023 - 01/2007
16	Cancer Pain 01/2023 - 10/2012
14	Constipation 01/2022 - 09/2003
13	Nausea 11/2022 - 09/2003
11	Vomiting 01/2023 - 09/2003
11	Delirium 01/2021 - 11/2013
9	Anorexia 01/2023 - 04/2014
8	Fatigue 10/2021 - 04/2013
8	Lung Neoplasms (Lung Cancer) 01/2021 - 08/2011
7	Heart Failure 01/2021 - 12/2010
6	Cachexia 01/2023 - 04/2014
6	Neuralgia (Stump Neuralgia) 02/2022 - 05/2013
5	Lung Diseases (Lung Disease) 12/2020 - 09/2008
5	Chronic Pain 01/2018 - 01/2009
4	Sleepiness 03/2024 - 11/2013
4	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2023 - 01/2018
4	Chronic Disease (Chronic Diseases) 10/2021 - 06/2007
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2018 - 04/2014
3	Urinary Retention 01/2022 - 03/2011
3	Body Weight (Weight, Body) 01/2021 - 04/2014
3	Hypoxia (Hypoxemia) 01/2021 - 04/2013
3	Disease Progression 10/2012 - 03/2011
2	Major Depressive Disorder (Major Depressive Disorders) 01/2023 - 01/2021
2	Opioid-Related Disorders (Opiate Addiction) 01/2023 - 12/2018
2	COVID-19 03/2021 - 01/2020
2	Opioid-Induced Constipation 01/2020 - 03/2013
2	Cardiovascular Diseases (Cardiovascular Disease) 03/2016 - 05/2015
2	Obesity 01/2016 - 01/2011
2	Sudden Death 01/2016 - 09/2015
2	Respiratory Insufficiency (Respiratory Failure) 01/2014 - 09/2011
1	Dementia (Dementias) 04/2024
1	Peptic Ulcer (Peptic Ulcers) 01/2023
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2023
1	Gastroesophageal Reflux (GERD) 01/2023
1	Ascites 10/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 02/2022
1	Dizziness (Lightheadedness) 01/2022

Drug/Important Bio-Agent (IBA)

48	Opioid Analgesics (Opioids)IBA 02/2024 - 09/2003
40	Morphine (MS Contin)FDA LinkGeneric 03/2024 - 09/2003
19	Oxygen (Dioxygen)IBA 10/2021 - 01/2006
7	Ketamine FDA LinkGeneric 01/2023 - 10/2012
6	BenzodiazepinesIBA 01/2021 - 11/2010
6	N-acetyltalosaminuronic acid (NAT)IBA 01/2021 - 03/2012
6	Haloperidol (Haldol)FDA LinkGeneric 12/2019 - 11/2013
5	anamorelinIBA 01/2023 - 04/2014
5	Octreotide (Sandostatin)FDA LinkGeneric 10/2020 - 01/2008
4	Antipsychotic Agents (Antipsychotics)IBA 01/2021 - 11/2013
3	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2023 - 05/2015
3	Analgesics (Analgesic Drugs)IBA 01/2023 - 07/2007
3	Pregabalin (Lyrica)FDA Link 02/2022 - 09/2015
3	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021 - 09/2016
3	AntiemeticsIBA 12/2019 - 10/2012
3	Sertraline (Zoloft)FDA LinkGeneric 01/2019 - 11/2016
3	Ghrelin ReceptorsIBA 08/2017 - 04/2014
3	Scopolamine (Hyoscine)FDA Link 12/2016 - 01/2008
2	Antidepressive Agents (Antidepressants)IBA 01/2023 - 01/2021
2	SmokeIBA 01/2022 - 01/2011
2	SolutionsIBA 01/2020 - 01/2017
2	Naloxone (Narcan)FDA LinkGeneric 01/2020 - 10/2019
2	Oxycodone (Oxycontin)FDA LinkGeneric 01/2020 - 01/2020
2	GlucocorticoidsIBA 12/2019 - 12/2018
2	methylnaltrexone FDA Link 10/2019 - 03/2013
2	Opioid Receptors (Opioid Receptor)IBA 10/2019 - 05/2015
2	SilverIBA 01/2018 - 04/2010
2	Growth Hormone (Somatotropin)IBA 08/2017 - 04/2014
2	butyl bromideIBA 12/2016 - 05/2015
2	Methylphenidate (Ritalin)FDA LinkGeneric 09/2015 - 04/2013
2	Gabapentin (Neurontin)FDA LinkGeneric 09/2015 - 09/2015
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 05/2015 - 01/2007
2	Metoclopramide (Reglan)FDA LinkGeneric 09/2014 - 10/2012
2	Anti-Anxiety Agents (Anxiolytics)IBA 07/2013 - 01/2012
2	Anesthetics (Anesthetic Agents)IBA 10/2012 - 01/2009
2	Furosemide (Lasix)FDA LinkGeneric 01/2012 - 01/2006
1	Testosterone (Sustanon)FDA Link 01/2023
1	LipidsIBA 01/2023
1	Cyclizine (Marezine)FDA Link 11/2022
1	Duloxetine Hydrochloride (Cymbalta)FDA Link 02/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	Amitriptyline (Elavil)FDA LinkGeneric 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2022
1	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 01/2022
1	Methadone (Dolophine)FDA LinkGeneric 01/2022
1	Nortriptyline (Aventyl)FDA LinkGeneric 01/2022
1	GlucuronidesIBA 01/2022

Therapy/Procedure

115	Palliative Care (Palliative Therapy) 01/2023 - 02/2006
28	Therapeutics 02/2023 - 09/2008
9	Drug Therapy (Chemotherapy) 02/2023 - 08/2011
9	Terminal Care (Care, Terminal) 02/2022 - 02/2007
4	Ambulatory Care (Outpatient Care) 01/2023 - 01/2021
4	Activities of Daily Living (ADL) 01/2021 - 06/2010
4	Hospice Care (Care, Bereavement) 01/2020 - 04/2010
2	Subcutaneous Infusions 01/2023 - 08/2015
2	Episode of Care 02/2015 - 06/2007
2	Analgesia 12/2012 - 10/2012
1	Long-Term Care 04/2024
1	Pain Management 01/2023